SPO entirely in English is for students that choose the “Politics and economics” curriculum.

However, if you are sufficiently proficient in English (C1), you can even take single courses in English instead of the traditional Italian edition (but specific rules apply to the courses in Statistics, Microeconomics and Macroeconomics)

Link to the syllaby on the website of the Facoltà di Scienze politiche economiche e sociali for the AY 2017/18.